TY - JOUR AU - Silveiro, Sandra Pinho AU - Zelmanovitz, Themis PY - 2018 TI - Does twenty-four-hour biological variation of serum creatinine and cystatin C influence GFR estimation? JF - Journal of Laboratory and Precision Medicine; Vol 3 (August 2018): Journal of Laboratory and Precision Medicine Y2 - 2018 KW - N2 - In the evolution process, moving from the marine environment challenged organisms to adapt to terrestrial conditions. This increased the requirement of the kidney regarding urine concentration abilities and tubular reabsorption of solutes, while coping with day/night cycles (1). In this sense, glomerular filtration rate (GFR) and tubular function were proved to be strongly related to a circadian rhythm (2). UR - https://jlpm.amegroups.org/article/view/4442