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Next generation sequencing as the new gold standard for minimal residual disease detection in B-ALL

   
@article{JLPM4610,
	author = {Rosa Ayala and Esther Onecha},
	title = {Next generation sequencing as the new gold standard for minimal residual disease detection in B-ALL},
	journal = {Journal of Laboratory and Precision Medicine},
	volume = {3},
	number = {0},
	year = {2018},
	keywords = {},
	abstract = {Cheng et al. (1) in their study explored the use of the next-generation sequencing (NGS) technology to evaluate post-remission minimal residual disease (MRD) in B acute lymphoblastic leukaemia/lymphoma (B-ALL) patients and its potential to be implemented in clinical settings. The authors propose an NGS-based method with an applicability of around 90% of B-ALL patients and a sensitivity of up to 10−6 and losing only 6.25% of the cases where leukaemia-specific clonotypes were not identified.},
	issn = {2519-9005},	url = {https://jlpm.amegroups.org/article/view/4610}
}