TY - JOUR AU - Wan, Jianxin AU - Su, Jiachun AU - Ye, Zhuangjian AU - Huang, Chumei AU - Liang, Jianbo AU - Liu, Min AU - Luo, Jinmei AU - Li, Laisheng PY - 2019 TI - Diagnostic performance of protein induced by vitamin K absence II for chronic hepatitis B-related hepatocellular carcinoma JF - Journal of Laboratory and Precision Medicine; Vol 4 (March 2019): Journal of Laboratory and Precision Medicine Y2 - 2019 KW - N2 - Background: The aim of this study was to assess the diagnostic value of prothrombin induced by vitamin K absence-II (PIVKA-II) for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) in a Chinese population. Methods: In this study, receiver operating characteristics (ROC) curve was plotted, and the area under the ROC curve (AUC) was calculated to assess the diagnostic performance of serum PIVKA-II levels for HBV-related HCC (n=134) with negative or mildly elevated α-fetoprotein (AFP) relative to chronic hepatitis B (CHB, n=119) patients or healthy controls (n=100). Results: Serum levels of PIVKA-II were significantly greater in the HBV-related HCC patients compared to the CHB patients (P UR - https://jlpm.amegroups.org/article/view/4931