Performance evaluation of the DiaSorin faecal calprotectin assay in monitoring inflammatory bowel disease: a diagnostic accuracy and comparative study

Faecal calprotectin (FC) is a widely used non-invasive marker for assessing intestinal inflammation in patients with inflammatory bowel disease (IBD). Previous studies indicate variability in FC results between manufacturers and it is possible that the clinical utility of FC is influenced by the analytical method used. Nevertheless, clinical pathways have been generated from a single FC method and applied widely. This study evaluates the DiaSorin method’s impact on patient classification using Buhlmann assay-derived cut-offs and assesses their clinical validity in IBD monitoring