Detection of membrane antigens of extracellular vesicles by surface plasmon resonance

Extracellular vesicles (EVs) are membrane-bound vesicles released from cells to the extracellular milieu, playing an important role in the biological processes, including intercellular communications (1). EVs can be generally divided into exosomes, microvesicles (MVs), and apoptotic bodies largely by their size, despite debate about their definition (2).